Offensive line question?

Was wondering if anyone else uses the o-line slide protect before they run the ball?

Like aggressive for HB dives, and left or right, if you are running left or right?

does anybody try this?

and is there a noticeable difference from doing this and not doing it?

I do it in practice when I'm working on different runs, but I usually get too into games to remember to implement it. Looking forward to input from more experienced players.