The 46 is a very dynamic pb that opens alot of opportunities for blitzing. Honestly I can sit here and type up 5 or 6 blitzes and tell u the setup but that wudnt help, just watch gibs' episode of madDen TV where he gives u his full defensive breakdown. He not only tells u which blitz work but more importantly why they work. It's all about numbers, bring 3 rushers at 2 defenders and confusing the other side of the line with a contain or fake blitz. Just watch the episode and i guarantee that it will open your eyes to how this game is played defensively. If u watch and r still having a hard time and u play on xbox, leave ur GT and I will happily lab it out with u.